Ageing is a complex process that occurs at a biological, cellular, and systemic level. Some age-related changes are harmless, such as graying hair. Whereas others can
impact us significantly, like reduced sensory function, decreased capacity for daily activities, and heightened susceptibility to frailty, disability, and chronic disease.
Ageing is not a disease, but advancing age is a major risk factor for disease. Additionally, many diseases accelerate the aging process. We see for instance that as life expectancy rises globally, there is a higher prevalence of chronic degenerative conditions, notably noncommunicable diseases (NCDs) like cardiovascular disease, neurodegenerative diseases, cancer, and diabetes.
By slowing the process of aging, it may therefore be possible to reduce the burden of age-related disease and increase health expectancy—that is, living well for longer.
However, to create effective interventions that support vitality with age, it is essential to first understand the aging process and factors that determine who ages ‘well’ or who is more susceptible to age-related disease.
